HIV Vaccine Human Trials Begin

(Los Angeles, California) Human trials have begun on a potential new AIDS vaccine that researchers describe as 'promising'.

The trials of the vaccine, called EP HIV-1090 were launched by the HIV Vaccine Trials Network (HVTN) and are being conducted in both the US and Botswana.

HVTN says it is the first trial to be conducted simultaneously in the US and Africa and the first HVTN trial to take place in Africa.

"This trial marks a new stage in global HIV research," stated Dr Larry Corey, Principal Investigator for the HVTN. "Africa is carrying the greatest burden of the Aids epidemic, and it is therefore crucial that HIV vaccine development include African leadership, participation and support."

EP HIV-1090 is assembled from synthetically produced DNA by Epimmune, a San Diego, California based pharmaceutical company.

The small pieces of DNA manufacture specific proteins like the ones in HIV. These proteins have elements referred to as epitopes, which in this case prepare the body to recognize real HIV.

There is no way that any part of this vaccine candidate can cause HIV infection the company said Thursday. As the body learns to mount a defense against the vaccine, the hope is that it will also learn to fight off real HIV, should the body ever be exposed to the actual virus.

The double-blinded trial is using 42 volunteers, 36 of whom will receive the candidate vaccine and six of whom will receive a placebo.

The trial will last 18 months, after which time the data will be evaluated. The candidate vaccine will then be considered for the next stage of testing.

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